Steroid Control of Acute Middle Ear Inflammation in a Mouse Model
نویسندگان
چکیده
منابع مشابه
Steroid control of acute middle ear inflammation in a mouse model.
OBJECTIVE To investigate steroids for their potential for therapeutic approaches to control otitis media. Glucocorticoids and mineralocorticoids have differential effects on inflammation and fluid absorption, but little is known of their control of middle and inner ear manifestations of acute otitis media. DESIGN Both glucocorticoid (prednisolone and dexamethasone) and mineralocorticoid (aldo...
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Acute inflammation of the middle ear (also referred to below as " acute otitis media ") is generally defined as acute, short-term, clinically confirmed inflammation in the middle ear. Second to the common cold, acute otitis media is the most common infectious disease among children. Mainly small children are affected; prior to 2 years of age, approximately 50% of children have at least one epis...
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The comparative anatomy of the pig middle ear cavity: a model for middle ear inflammation in the human?
This study was undertaken to develop a functional model of otitis media with effusion (OME) in the pig (Sus scrofa), with the purpose of investigating the origin of lymphocytes populating the middle ear during the course of an inflammatory process. The relevance of the model to the human condition of OME is to a large extent dependent on the anatomical and physiological similarities between the...
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ژورنال
عنوان ژورنال: Archives of Otolaryngology - Head and Neck Surgery
سال: 2009
ISSN: 0886-4470
DOI: 10.1001/archoto.2009.23